. 2018 Jan 29;96(2):579–590. doi: 10.1093/jas/skx076

Table 5.

Effect of CLA supplementation on concentrations of CLA and arachidonic acid in synovial fluid

Fatty acid, mg/100 mg total fatty acids	Day	Treatment^a			SEM	P-values
Fatty acid, mg/100 mg total fatty acids	Day	CON	LOW	HIGH	SEM	Trt^b	Time	Contrast^c
cis-9, trans-11 CLA	0	0.00	0.00	0.00	0.08	<0.01	<0.01	<0.01
	28	0.00^a	0.22^a	0.73^b
	42	0.00^a	0.35^b	0.62^c
	56	0.00^a	0.48^b	0.79^c
trans-10, cis-12 CLA	0	0.00	0.00	0.00	0.08	<0.01	<0.01	<0.01
	28	0.00^a	0.18^a	0.69^b
	42	0.00^a	0.35^b	0.62^c
	56	0.00^a	0.43^b	0.81^c
Arachidonic acid	0	1.16	1.29	1.25	0.2	0.06	<0.01	0.22
	28	1.04	0.61	0.77
	42	1.47^a	0.93^b	0.8^b
	56	1.35^a	1.15^a	0.86^b

^aCON = 1% diet soybean oil; LOW = 0.5% diet soybean oil, 0.5% diet CLA; HIGH = 1% diet CLA.

^bTrt = main effect of treatment for the 56-d trial.

^cContrast = quadratic response of dietary treatments to d 42, prior to the LPS challenge.

^a-cSuperscripts denote differences between dietary treatments (P < 0.05).