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. 2018 Feb 19;96(4):1495–1507. doi: 10.1093/jas/sky029

Table 2.

Differential expression of genes in the livers of fattening lambs allowed ADL or RES milk intake during the suckling period

Gene ID and function Description TPMa mean ADL TPMa mean RES log2FCb P-value FDRc
LOC101110202 Cytochrome P450 3A24-like 508 749 0.433 8.45E-08 0.0005
CYP2C19 Cytochrome P450 2C19 347 819 0.708 3.48E-05 0.0218
CYP3A24 Cytochrome P450 CYP3A24 1,150 1,956 0.548 6.48E-05 0.0304
CDC37L1 Cell division cycle 37 like 1 15 22 0.381 2.35E-06 0.0026
APOH Apolipoprotein H 5,423 4,484 −0.359 9.67E-06 0.0091
F2 Coagulation factor II, thrombin 1,270 1,038 −0.366 1.00E-04 0.0433
TF Serotransferrin 9,775 7,643 −0.420 1.75E-05 0.0123
GUCY2C Guanylate cyclase 2C 5 12 0.619 4.30E-04 0.0893
ACSM3 Acyl-CoA synthetase medium-chain family member 3 755 604 −0.382 3.00E-04 0.0877
ACOT13 Acyl-CoA thioesterase 13 166 128 −0.419 4.20E-04 0.0893
ACOX3 Acyl-CoA oxidase 3, pristanoyl 44 28 −0.561 4.80E-04 0.0893
FADS6 Fatty acid desaturase 6 186 136 −0.459 5.20E-04 0.0893
ND3 NADH dehydrogenase subunit 3 1,751 1,057 −0.686 3.21E-07 0.0005
APOM Apolipoprotein M 121 96 −0.392 2.30E-04 0.0843
ABCA10 ATP binding cassette subfamily A member 10 118 96 −0.364 6.50E-04 0.0972
CST3 Cystatin C 314 222 −0.515 5.22E-05 0.0280
SERPINA11 Serpin family A member 11 235 199 −0.318 4.70E-04 0.0893
DNAJA1 DnaJ heat shock protein family member A1 14 21 0.422 4.10E-04 0.0893
LOC101105132 DnaJ homolog subfamily A member 1 24 37 0.430 4.20E-04 0.0893
LOC105605968 d DnaJ homolog subfamily A member 1 36 56 0.468 5.47E-05 0.0280
LOC101101922 d DnaJ homolog subfamily A member 1 29 46 0.474 2.90E-04 0.0877
LOC101102122 d 60S acidic ribosomal protein P1 596 471 −0.420 3.84E-07 0.0005
RPLP1 Ribosomal protein lateral stalk subunit P1 871 692 −0.403 1.37E-05 0.0110
RPL3 Ribosomal protein L3 548 494 −0.245 2.90E-04 0.0877
LOC101114033 60S ribosomal protein L17 208 179 −0.297 6.50E-04 0.0972
DPYS Dihydropyrimidinase 358 233 −0.541 4.20E-04 0.0893
ACP5 Acid phosphatase 5, tartrate resistant 82 56 −0.571 3.55E-07 0.0005
RBMS2 RNA binding motif single stranded interacting protein 2 8 6 −0.436 4.50E-04 0.0893
SERINC2 Serine incorporator 2 13 28 0.633 2.40E-04 0.0843
GCAT Glycine C-acetyltransferase 190 139 −0.454 6.60E-04 0.0972
NUFIP2 NUFIP2, FMR1 interacting protein 16 25 0.454 2.40E-04 0.0843
PLXNA2 Plexin A2 4 2 −0.555 5.70E-04 0.0911
LOC101106024 Secreted and transmembrane protein 1A-like 47 92 0.592 3.30E-04 0.0893
ELK4 ELK4, ETS transcription factor 10 14 0.402 5.40E-04 0.0893
EPS8 Epidermal growth factor receptor pathway substrate 8 10 14 0.363 5.40E-04 0.0893
C1H21orf33 Chromosome 1 open reading frame, human C21orf33 161 126 −0.399 5.00E-04 0.0893
LOC101121401 d Ferritin heavy chain 273 227 −0.344 4.80E-04 0.0893
CCDC117 Coiled-coil domain containing 117 16 22 0.344 5.30E-04 0.0893

aTPM = Transcripts Per Kilobase Million.

bFold change estimates are relative to ADL group, so positive values indicate greater expression in RES lambs.

cFDR = false discovery rate.

dNonexpressed pseudogenes.