Skip to main content
. 2018 Feb 19;96(4):1495–1507. doi: 10.1093/jas/sky029

Table 3.

Annotation clusters identified by the Functional Annotation Tool of DAVID from the list of 38 differentially expressed genes [DESeq2 (P. BH < 0.10)]

Term No.a P-value Genes symbolsb
Annotation cluster 1
Enrichment score: 1.900
 Cytochrome P450, conserved site 3 0.002 CYP2C19, CYP3A24, LOC101110202
 Cytochrome P450 3 0.003 CYP2C19, CYP3A24, LOC101110202
 Monooxygenase 3 0.004 CYP2C19, CYP3A24, LOC101110202
 Oxidoreductase 4 0.005 CYP2C19 , ND3, CYP3A24, LOC101110202
 Heme 3 0.009 CYP2C19, CYP3A24, LOC101110202
 Iron 3 0.020 CYP2C19, CYP3A24, LOC101110202
 Heme binding 3 0.026 CYP2C19, CYP3A24, LOC101110202
 Iron ion binding 3 0.034 CYP2C19, CYP3A24, LOC101110202
 Metal-binding 3 0.560 CYP2C19, CYP3A24, LOC101110202
Annotation cluster 2
Enrichment score: 0.440
 Ribosomal protein 3 0.014 RPLP1, LOC101114033, RPL3
 Ribonucleoprotein 3 0.017 RPLP1, LOC101114033, RPL3
 Structural constituent of ribosome 3 0.074 RPLP1, LOC101114033, RPL3
 Ribosome 3 0.100 RPLP1, LOC101114033, RPL3
Annotation cluster 3
Enrichment score: 0.090
 Membrane 8 0.700 FADS6, ABCA10, GUCY2C , ND3, CYP3A24, LOC101110202, SERINC2, PLXNA2
 Transmembrane helix 7 0.810 FADS6, ABCA10, GUCY2C , ND3, LOC101110202, SERINC2, PLXNA2
 Transmembrane 7 0.820 FADS6, ABCA10, GUCY2C , ND3, LOC101110202, SERINC2, PLXNA2
 Integral component of membrane 6 0.910 FADS6, ABCA10, GUCY2C , ND3, LOC101110202, SERINC2

aNumber of genes involved.

bDifferentially expressed genes up-regulated in the early feed restricted group are marked in bold.