Table 5.
List of identified metabolites up- or down-accumulated in plasma samples from early feed RES fattening lambs when compared with those fed ADL during the suckling period
Metabolite | P (corr)a | FCb | Regulationc |
---|---|---|---|
Lipid metabolites | |||
3-Oxohexacosanoic acid | 0.096 | 23 | down |
1-Linoleoyl Glycerol | 0.025 | 435 | down |
MG(0:0/14:0/0:0) | 0.002 | 529 | up |
1-Monopalmitin | 8.91E-09 | 16,522 | up |
DG(16:0/16:0/0:0) | 0.013 | 1,699 | up |
PI(22:1(11Z)/0:0) | 9.68E-04 | 1,005 | up |
PS(14:1(9Z)/14:1(9Z)) | 4.43E-06 | 8,888 | up |
PS(20:1(11Z)/0:0) | 0.020 | 72 | up |
PS(22:0/18:1(9Z)) | 0.001 | 234 | up |
3-Hydroxysuberic acid | 0.045 | 39 | up |
Methyl 4-[2-(2-formyl-vinyl)-3-hydroxy-5-oxo-cyclopentyl]-butanoate | 0.099 | 125 | up |
Steroid ester | |||
1,3,5(10)-Estratrien-2,3-dial-17-one2-methyl ether | 0.027 | 178 | down |
11β,17β-Dihydroxy-9α-fluoro-17α-methyl-5β-androstan-3- one | 2.28E-07 | 16,074 | up |
Sphingolipids | |||
C17 Sphinganine | 3.26E-04 | 1,545 | down |
Cer(t18:0/16:0) | 0.002 | 452 | up |
Vitamin D metabolism | |||
1α,25-dihydroxy-23,24-dinorvitamin D3 | 0.020 | 82 | up |
Aminoacid metabolism | |||
Ser Gly His | 0.085 | 39 | down |
Calpeptin | 0.025 | 98 | down |
NAc-FnorLRF-amide | 0.021 | 45 | up |
Phe His | 0.037 | 163 | up |
Others | |||
Melilotocarpan E | 0.004 | 742 | down |
Prosopinine | 0.011 | 204 | down |
Manoalide | 4.62E-05 | 3,227 | down |
Pinacidil | 0.045 | 147 | down |
Pymetrozine | 0.011 | 240 | down |
CAY10550 | 0.005 | 713 | down |
CAY10583 | 0.058 | 103 | down |
Panaxytriol | 0.001 | 295 | up |
Oxaprozin | 1.15E-04 | 1,409 | up |
p-Hydroxytiaprofenic acid | 8.27E-09 | 14,511 | up |
BILA 2185BS | 7.01E-10 | 12,745 | up |
Idebenone metabolite (benzenehexanoic acid, 2,5-dihydroxy-3,4-dimethoxy-6-methyl-) | 7.29E-04 | 2,235 | up |
2-Thio-Acetyl MAGE | 1.81E-09 | 7,094 | up |
Hemibrevetoxin B | 2.51E-07 | 4,557 | up |
β-L-Fucose 1-phosphate | 3.47E-05 | 2,374 | up |
7-Hydroxy-5-heptynoic acid | 0.012 | 324 | up |
7-Methyl-2-hydroxy-6-oxoocta-2,4-dienoate | 1.89E-04 | 1,777 | up |
Diethyl oxalpropionate | 0.075 | 140 | up |
aBonferroni multiple testing correction.
bFC = fold change.
cAnalysis is done considering RES vs. ADL; hence, “up” means that the compound is over-accumulated in RES, compared with ADL.