Table 2.
Myograph treatment | Vessel | Log EC50, M |
---|---|---|
TCB-2, M | MA | −4.79 ± 0.09 (7)3a |
MV | −5.23 ± 0.09 (7)b | |
RA | −4.63 ± 0.11 (6)a | |
RV | −5.29 ± 0.11 (6)b |
Values are expressed as the mean ± SEM.
a,bWithin a column for Log EC50, means without a common superscript differ (P < 0.05).
1Log EC50 = measure of the potency of a drug or agonist that induces a response midway (50%) between the baseline and maximum after a certain time of exposure; expressed as the molar concentration of the agonist, in this instance, 120 mM KCl.
2EC50 values were only considered for vessels exposed to TCB-2 as TCB-2 was the only agonist that elicited a vasoconstrictive response.
3Values in parentheses are the number of animals used in each experiment.