Table 2.
Presenting clinical problems of the study cohort (N = 11)
| Category | n (%) / mean (SD) |
|---|---|
| Bipolar disorder, n (%) | |
| Type 1 | 5 (45.5) |
| Type 2 | 6 (55.5) |
| Comorbidity and clinical course, n (%) | |
| History of Psychosis | 3 (27.3) |
| Current Depressive Episode | 5 (45.5) |
| Current Comorbid Anxiety Disorder | 9 (81.8) |
| Past Comorbid Anxiety Disorder | 2 (18.2) |
| Other Current Comorbid Axis I Disorder | 1 (9.1) |
| History of other Axis I Disorders | 6 (55.5) |
| Bipolar disorder variables, mean (SD) | |
| Age at onset, years | 19.18 (7.17); range: 13 – 35 |
| Number of episodes depression (past 6 months) | 0.45 (0.52); range: 0 – 1 |
| Duration of episodes depression (past 6 months) in weeks | 6.40 (5.18); range: 2 – 12 |
| Number of episodes (hypo)mania (past 6 months) | 0.27 (0.47); range: 0 – 1 |
| Duration of episodes (hypo)mania (past 6 months) in weeks | 1.67 (0.58); range 1 – 2 |
| Number of suicide attempt (lifetime) | 0.27 (0.47); range: 0 – 1 |
| Number of hospitalizations (lifetime) | 0.73 (0.77); range: 0 – 2 |
| Number of episodes depression (lifetime), n (%) | |
| 0 – 4 episodes: | 4 (36.4) |
| 5 – 9 episodes: | 2 (18.2) |
| 10 or more episodes: | 5 (45.5) |
| Medication at Screening, n (%) | |
| Lithium | 4 (36.4) |
| Anticonvulsants | 4 (36.4) |
| Antipsychotics | 7 (63.6) |
| Antidepressants | 1 (9.1) |
| Current Comorbid Anxiety Disorder, n (%) | |
| Posttraumatic stress disorder | 3 (27.3) |
| Generalized anxiety disorder | 3 (27.3) |
| Obsessive compulsive disorder | 1 (9.1) |
| Specific phobia | 1 (9.1) |
| Social anxiety | 4 (36.4) |
| Panic disorder | 1 (9.1) |
| Other Current Axis I Disorder, n (%) | |
| Substance dependence | 1 (9.1) |
| Past Comorbid Anxiety Disorder, n (%) | |
| Social anxiety | 1 (9.1) |
| Panic disorder | 1 (9.1) |
| History of other Axis I Disorder, n (%) | |
| Alcohol dependence | 1 (9.1) |
| Bulimia | 1 (9.1) |
| Anorexia | 3 (27.3) |
| Eating disorder NOS | 2 (18.2) |