Table 9.

All possible marker pairs in hKOR region that show most significant evidence for linkage disequilibrium in control subjects

Population	First marker	Second marker	Distancea	nb	Chi-square	P	Δ2	D′c
African-American	113G>A	36G>T	333	34	17.1	< 0.001	0.409	1
	113G>A	846C>T	21 741	34	20.2	< 0.001	0.561	1
	133G>A	843A>G	21 728	34	5.2	0.023	0.075	1
	36G>T	846C>T	21 408	34	6.58	0.01	0.161	0.47
	459C>T	843A>G	5313	34	7.29	0.007	0.198	1
	843A>G	846C>T	3	34	5.29	0.021	0.144	1
	846C>T	948C>T	102	34	12.81	< 0.001	0.362	1
Caucasian	113G>A	36G>T	333	64	21.23	0	0.266	1
	113G>A	843A>G	21 738	64	16.38	< 0.001	0.251	1
	113G>A	846C>T	21 741	64	34.38	0	0.85	1
	36G>T	846C>T	21 408	64	15.82	< 0.001	0.212	0.82
	459C>T	843A>G	5313	64	12.24	< 0.001	0.207	1
	843A>G	846C>T	3	64	19.24	< 0.001	0.295	1
	846C>T	948C>T	102	64	4.57	0.033	0.136	1
Hispanic	113G>A	846C>T	21 741	25	18.54	< 0.001	1	1
	113G>A	36G>T	333	25	13.19	< 0.001	0.574	1
	36G>T	846C>T	21 408	25	13.19	< 0.001	0.574	1
	459C>T	843A>G	5313	25	5.87	0.015	0.136	1

^aDistance is given in nucleotides from the indicated single nucleotide polymorphism (SNP) to the next SNP according to the map of chromosome 8 on 29 April 2004.

^bn, Number of individuals.

^cD′ values of 0.0 indicate that one of the two SNPs was not polymorphic in the particular population.