Table 1. Summary of Cases Reviewed in the Literature.
First Author (Ref.) | Year | Case | Description |
Harris [6] | 1969 | 27-year-old female | -No previous history of HTN or renal disease/No family history of HTN -Taking OCPs for 30 months which led to malignant HTN (BP = 220/150) -Within a month, her BP had fallen to 200/110 mm Hg after taking antihypertensive medications and stopped taking OCPs |
Zacherle et al. [7] | 1972 | 29-year-old female | -No previous history of HTN or renal disease/No family history of HTN -First time taking OCP was in 1967 and after one year, BP increased to 220/150, and by stopping OCP and taking antihypertensive medication, high BP dropped to normal after three months. Second time taking OCP was in 1970, and after one year, malignant HTN (BP = 250/190) led to irreversible renal failure |
Dunn et al. [8] | 1975 | 26-year-old female | -History of gestational HTN in 1960. Started OCP in 1964 and got malignant HTN (BP = 230/150) in 1966 -High BP was rapidly controlled after discontinuing OCP and taking antihypertensive medications |
Weir et al. [4] | 1971-1974 | A prospective study of 66 women | -High systolic BP after one year (between 115.1 +/- 1.3), high diastolic BP at the end of two years -Discontinuance of OCPs resulted in the return of BP to pretreatment levels within three months -No cases of severe or malignant HTN among patients. |