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. 2018 Sep 17;13(9):e0203944. doi: 10.1371/journal.pone.0203944

Fig 1. Intracellular reactive oxygen species (ROS) generation in the cartilage and synovium of patients with end-stage knee osteoarthritis (OA).

Fig 1

(A) Intracellular ROS generation in articular cartilage. Left and right panels show the findings of dihydroethidium (DHE) staining. Controls: anterior cruciate ligament reconstruction (ACLR) or medial meniscectomy (MM), Knee OA: total knee arthroplasty (TKA) (N = 6, ***P < 0.001 versus controls, Student’s t-test). Error bars show the mean ± standard deviation. (B) Intracellular ROS generation in synovium. Left and right panels show the findings of DHE staining. Controls: ACLR or MM, Knee OA: TKA (N = 6, *P < 0.05 versus controls, Student’s t-test). Error bars show the mean ± standard deviation.