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. 2018 Sep 17;13(9):e0204245. doi: 10.1371/journal.pone.0204245

Table 1. Key input parameters.

Description of parameter input Value References
Alcohol use
    Prevalence of unhealthy alcohol use (Male/Female) 9.7%/2% [29]
    Relative risk of unhealthy alcohol use on condom misuse or non-use 1.29 [30]
    Relative risk of unhealthy alcohol use on non-HIV STIs 1.72 [30]
    Relative risk of unhealthy alcohol use on non-adherence to ART 2.33 [30]
Sexual risk behaviors
    Proportion abstinent (M/F) 5%/10% [3134]
    Proportion monogamous (M/F) 31%/69% [3436]
    Proportion in multiple, concurrent relationships (M/F) 56%/17% Assumption
    Proportion who are clients of (men) or who are CSW (female) (M/F) 8%/4% [37, 38]
    Frequency of sex acts (per year) 104 Assumption
    Duration of relationship 1y-30y Assumption
    Median number of concurrent partners- non CSW 3 [36]
    Median number of concurrent partners- CSW 10 [36]
    Probability of consistent condom use 56.8% [39]
    Relative risk of unsafe sex (condom nonuse most or all of the time) if aware of HIV status 0.47 [40]
HIV epidemiology and transmission
    Adult HIV prevalence (1997) 20.9% [41]
    Probability of transmission per sex act 0.00011–0.01243 [42, 43]
    Prevalence of circumcision among adult men 20% [39]
    Modifier of male circumcision on F→M HIV transmission per sex act RR 0.6 [44]
    Modifier of consistent condom use on HIV transmission per sex act RR 0.2 [45]
    Untreated non-HIV STI prevalence 6% [46]
    Probability of HIV testing 40% [39]
    Probability of linkage to HIV care and treatment 50.3% [39]
    Probability of adherence to ART regimen 84% [47]
Intervention effects and costs
    Modifier of Intervention on Linkage and Retention RR 1.48 RCT
    Outpatient care, per year, no ART (visits, SMS, BCPP, Financial incentives) $324 RCT
    On Site CD4+ test available $26 RCT
Utilities
    Decrease in utility with ART 0.053 [48]
    Utility with CD4+ count < 50 cells/mm3 0.69 [49, 50]
    Utility with CD4+ count between 50 cells/mm3 and 199 cells/mm3 0.79 [50]
    Utility with CD4+ count ≥200 cells/mm3 0.83 [50]
Other Costs (2015 US$)
    Outpatient care, per year, without ART (non-intervention) $278 RCT
    Hospitalization costs, per year $464 [51]
    First-line ART, monthly $13 [52]
    Second-line ART, monthly $28 [52]
    Viral load test $35 [53]
    CD4+ count test (non-intervention) $11 RCT

Abbreviations: STI, Sexually transmitted infection; CSW, Commercial sex worker; SMS, text messaging; BCPP, Basic care and prevention package