Table 1.
The relationship between miR-300 and the clinicopathologic characteristics in OSCC patients
| Patient characteristics | No of patients | miR-300 low expression (≤median) n (%) | miR-300 high expression (>median) n (%) | χ2 value | P-value |
|---|---|---|---|---|---|
| Patients included | 120 | 78 (100) | 42 (100) | ||
| Gender | |||||
| Male | 65 | 40 (51.3) | 25 (59.5) | 0.747 | |
| Female | 55 | 38 (48.7) | 17 (40.5) | ||
| Age (years) | |||||
| ≤55 | 50 | 36 (46.2) | 14 (33.3) | 1.846 | |
| >55 | 70 | 42 (53.8) | 28 (66.7) | ||
| Primary tumor site | |||||
| Buccal | 24 | 16 (20.5) | 8 (19.0) | 2.447 | |
| Tongue | 52 | 37 (47.5) | 15 (35.7) | ||
| Gingival | 25 | 15 (19.2) | 10 (23.8) | ||
| Other | 19 | 10 (12.8) | 9 (21.5) | ||
| Differentiation | |||||
| Well/moderate | 59 | 38 (48.7) | 21 (50.0) | 0.018 | |
| Poor | 61 | 40 (51.3) | 21 (50.0) | ||
| T classification | |||||
| T1/2 | 52 | 20 (25.6) | 32 (76.2) | 28.41 | <0.01 |
| T3/4 | 68 | 58 (74.4) | 10 (23.8) | ||
| N classification | |||||
| N0 | 40 | 19 (24.4) | 21 (50.0) | 8.077 | <0.01 |
| N1–3 | 80 | 59 (75.6) | 21 (50.0) | ||
| M classification | |||||
| M0 | 69 | 35 (44.9) | 34 (81.0) | 14.543 | <0.01 |
| M1 | 51 | 43 (55.1) | 8 (19.0) |
Abbreviation: OSCC, oral squamous cell carcinoma.