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. 2018 Aug 23;3(16):e120794. doi: 10.1172/jci.insight.120794

Figure 5. Reduced hepatic steatosis correlates with Aloxe3-induced fasting responses.

Figure 5

(A) Oil Red O staining in livers from low-fat or high–trans fat/cholesterol–fed mice overexpressing GFP or Aloxe3. (B–D) Hepatic tissue quantification of triglycerides, LDL-C, total cholesterol in low-fat or high–trans fat/cholesterol–fed mice overexpressing empty vector or Aloxe3. (E) Serum albumin measurements in mice analyzed in A–D Number of mice in each group is: 5, AAV8GFP LFD; 10, AAV8GFP HTFC; 5, AAV8ALOXE3 LFD; and 10, AAV8ALOXE3 HTFC. Scale bar: 100 μm. **P < 0.01 and ****P < 0.0001 by 2-tailed t test with Bonferroni-Dunn post hoc correction versus untreated controls group or versus the bracketed comparison group where indicated.