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. 2018 Aug 23;3(16):e121522. doi: 10.1172/jci.insight.121522

Figure 1. Potentially immunogenic ERVs are abundant in 4 solid cancers from TCGA.

Figure 1

(A) Immune checkpoint activation criteria used to identify potentially immunogenic ERVs (πERVs) in each solid cancer type. (B) The number of πERVs in each solid cancer type identified 4 cancer types with an unusually high number of πERVs. (C) Correlation (Spearman) between expression of πERVs (rows) and levels of immunological variables (columns) in the 4 cancer types. (D) ERV3-2 was identified as a πERV in 11 different cancer types. Cancer type acronyms are standard TCGA abbreviations (https://tcga-data.nci.nih.gov/).