Table 2. Optimized work loops.
Muscle length (ML) change amplitude and frequency of large amplitude sinudoidal oscillations were varied until maximum power generating parameters were obtained. fPmax: the frequency at which maximum power was generated as determined using the work loop technique. Student’s t-test with p<0.05 significantly different from control (*p<0.05, **p<0.01, ***p<0.001) or heterozygote (xp<0.05, xxp<0.01, xxxp<0.001). N = 12 for control and mutant heterozygotes; N = 16 for mutant homozygotes. Full genotypes given in legend to Table 1.
| Line | Power (W/m3) |
Net work (J/m3) | Work Gen. (J/m3) | Work abs. (J/m3) | % ML Amplitude | fPmax (Hz) |
|---|---|---|---|---|---|---|
| PwMhc2 control | 240 ± 34 | 2.18 ± 0.3 | 36.16 ± 4.19 | 33.98 ± 3.95 | 0.79 ± 0.06 | 115 ± 8 |
| R146N-15/+ heterozygote | 137 ± 20* | 0.93 ± 0.1*** | 21.92 ± 2.70** | 20.99 ± 2.59** | 0.5 ± 0.03*** | 150 ± 5** |
| R146N-15 homozygote | 85 ± 7***x | 0.65 ± 0.06*** | 22.50 ± 1.51** | 21.84 ± 1.46** | 0.52 ± 0.03*** | 130 ± 3xx |