Table 2.
Clinical profile and periictal MRI and EEG findings of 9 patients of Study 2.
| Case No. | Age/Sex | Clinical diagnosis | Epileptogenic lesion | Seizure |
IV Medi-cation | Timing of MRI | ASL with dual PLD findings |
DWI findings | Subsequent EEG findings | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Type | Approximate duration | Epilepto-genic lesion | Epileptically activated area | Spreading area | ||||||||
| Group EL+ | ||||||||||||
| 2 | 46/M | Symptomatic partial epilepsy | Old contusion Bifrontal apicies | Generalized seizure | 1 h | DZP MDZ fPTH | 1 h | Hypo-signal | Bifrontal, Interhemispheric; Fast flow type | – | – | Generalized slow |
| 3 | 83/M | Symptomatic partial epilepsy | Old contusion Lt.fronto-parietal | Tonic seizure Rt. Face& Upper limb | 1 h intermittent | DZP fPTH | 2 days | Hypo-signal | Lt. fronto-parietal; Fast flow type | – | – | No paroxysms |
| 4 | 70/M | Symptomatic partial epilepsy | Old ICH Lt. frontal | Rt. Facial seizure | 3 days intermittent | DZP fPTH LEV | 1 day | Hypo-signal | Lt frontal; Fast flow type | – | – | No paroxysms |
| 5 | 87/F | Symptomatic partial epilepsy | Clipped Acom aneurysm | Generalized seizure | Several minutes | DZP fPTH LEV | 1 day | ? (Clip artifact) | Bifrontal, Interhemispheric; Fast flow type | – | – | Generalized slow |
| 6 | 76/M | Symptomatic partial epilepsy | Recurrent PML Rt. Frontal base | Generalized seizure | Several minutes (twice) | DZP LEV | Within 30 min | ? (Small lesion) | Rt. Frontal; Fast flow type | Generalized Predominantly Rt; Fast flow type | + (See text) | Not examined |
| 7 | 80/F | Symptomatic partial epilepsy | Convexity meningioma Rt. Frontal | Tonic seizure Lt. Face& Upper limb | Several minutes | DZP, fPTH, LEV | 1 day | Hyper-signal | Rt. Frontal; Fast flow type | Bifrontal, Interhemispheric; Fast flow type | – | Not examined |
| Group EL− | ||||||||||||
| 8 | 80/M | Situation-related seizure | -*Hyponatoremia Chronic alcoholism | Generalized seizure | Several minutes(3 times) | DZP, MDZ | 1 day | – | Bil. Frontal; Gradual flow type | – | – | Subclinical seizure activities at F4&C4 |
| 9 | 81/F | Situation-related seizure | -* Hyponatoremia Diabetus mellitus | Generalized seizure | Several minutes (twice) | DZP, fPTH | 2 days | – | Bil. Frontal; Gradual flow type | – | – | Not examined |
| 10 | 77/M | Non-lesional elderly epilepsy | -* | Generalized seizure | Several minutes (twice) | DZP, MDZ | 1 h | – | Lt. frontal base; Gradual flow type | Rt. Frontal, Interhemispheric; Fast flow type | – | Generalized slow+** |
Abbreviations of this table: MRI, magnetic resonance imaging; EEG, electroencephalography; ASL, arterial spin labeling; PLD, dual postlabeling delay; DWI, diffusion weighted image; IV, intravenous; EL, epilleptogenic lesion; M, male; F, female Lt, left; Rt, right; ICH, intracerebral hemorrhage; Acom, anterior communicating artery; PML, primary malignant lymphoma; −*, no epileptogenic lesion but with subcortical T2 prolonged lesion; DZP, diazepam; MDZ, midazolam; fPHT, fosphenytoin; LEV, levetiracetum; min, minutes; −, negative; +, positive; **, absence of α rhythm on Lt frontal region.