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. 2018 Sep 14;24(34):3884–3897. doi: 10.3748/wjg.v24.i34.3884

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©The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.

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Forced expression of FMNL3 promotes colorectal carcinoma cell proliferation, invasion, and migration in vitro. A and B: Identification of FMNL3 expression in FMNL3-overexpressing cells by real-time quantitative PCR and western blot. C: Effects of FMNL3 overexpression on cell proliferation by MTT assay. D: Effects of FMNL3 overexpression on invasive abilities by Boyden chamber assay. Morphological comparison of cell penetration into the artificial basement membrane is shown. E: Effects of FMNL3 overexpression on migratory abilities by scratch assay in vitro. Scale bars represent 50 μm (cell invasion assay) or 100 μm (cell migration assay), respectively. ^aP < 0.001, ^bP < 0.01 and ^cP < 0.05 vs NC or mock group. Error bars indicate mean ± SD.