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. 2018 Sep 14;24(34):3884–3897. doi: 10.3748/wjg.v24.i34.3884

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©The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.

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Effects of formin-like 3 overexpression (A and B) and depletion (C) on filopodia and lamellipodia in colorectal carcinoma cells. Cells are displayed using tritc-phalloidine (F-actin, Red) and DAPI (nuclear, blue) staining, and laser scanning confocal microscopy detection. Enlarged views of the boxed regions are shown on the right side of the figures. Blue arrows indicate filopodia, yellow arrows indicate lamellipodia. Scale bars represent 5 μm. ^aP < 0.001, and ^bP < 0.01 vs mock or scramble group. Error bars indicate mean ± SD. FMNL3: Formin-like 3.