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. Author manuscript; available in PMC: 2019 Aug 1.
Published in final edited form as: Curr Opin Immunol. 2018 Jun 22;53:196–202. doi: 10.1016/j.coi.2018.05.001

Figure 2. Visualization of the Mucin-Like Domain.

Figure 2

(A) The crystal structure of the mucin-deleted EBOV GP (PDB: 5JQ3) [65] is shown docked into a subtomogram averaged map of mucin-deleted EBOV GP [66] and a single-particle generated map of intact, mucin-containing EBOV GP (B) [22]. Although the observation of density for mobile regions is limited by technical factors in single particle reconstruction, the regions of the mucin-like domain that are visible appear to extend upwards and outwards from the glycan cap and base region, thereby shielding much of the GP core.