Table 3.
Data analysis by using a Cox regression model with survival data censored at 28 days and then censored at 90 days in succession
| Inclusion d28 | Inclusion d90 | |||||||
|---|---|---|---|---|---|---|---|---|
| HR | 95% CI | p value | HR | 95%CI | p value | |||
| Univariate Cox model (universal analysis) | ||||||||
| Sex (F vs M) | 1.59 | 1.12 | 2.24 | 0.013 | 1.51 | 1.06 | 2.14 | 0.021 |
| Weight (per 10 kg increase) | 1 | 0.89 | 1.13 | 0.999 | 1.04 | 0.93 | 1.16 | 0.503 |
| pH (per 0.1 increase) | 0.97 | 0.95 | 0.98 | < 0.001 | 0.97 | 0.95 | 0.98 | < 0.001 |
| Hyperoxia vs normoxia | 1.44 | 1.00 | 2.07 | 0.051 | 1.28 | 0.91 | 1.82 | 0.160 |
| SAPS 2 | 1.05 | 1.03 | 1.06 | < 0.001 | 1.05 | 1.04 | 1.06 | < 0.001 |
| Mac Cabe | 1.25 | 0.97 | 1.62 | 0.089 | 1.25 | 0.98 | 1.61 | 0.073 |
| PaO2/FiO2 | 1 | 0.99 | 1.00 | 0.860 | 1 | 0.99 | 1.00 | 0.660 |
| Autoimmune disease | 1.17 | 0.76 | 1.80 | 0.480 | 1.262 | 0.84 | 1.89 | 0.260 |
| Multivariate Cox model | ||||||||
| Sex (F vs M) | 1.55 | 1.06 | 2.27 | 0.022 | 1.53 | 1.06 | 2.22 | 0.024 |
| pH (per 0.1 increase) | 0.96 | 0.95 | 0.98 | < 0.001 | 0.97 | 0.95 | 0.98 | < 0.001 |
| Hyperoxia vs normoxia | 1.79 | 1.21 | 2.63 | 0.003 | 1.57 | 1.09 | 2.28 | 0.016 |
| SAPS 2 | 1.05 | 1.04 | 1.06 | < 0.001 | 1.05 | 1.04 | 1.06 | < 0.001 |
| Mac Cabe | 1.07 | 0.82 | 1.39 | 0.613 | 1.06 | 0.83 | 1.37 | 0.640 |
HR hazard ratio, CI confidence interval, F female, M male