Table 2.
Variable | Number of samples with H-score >50/total (%) | p value vs normala,b | Other (p value)a,b |
---|---|---|---|
All samples | |||
Normal breast | 2/7 (29) | ||
Ductal carcinoma | 86/100 (86) | 0.0018 | |
Grade | |||
2 | 46/54 (85) | 0.0035 | |
3 | 36/42 (86) | 0.004 | |
Tumor invasion | |||
T1 | 8/10 (80) | 0.0584 | |
T2 | 55/62 (89) | 0.0012 | |
T3 | 14/16 (88) | 0.0107 | |
T4 | 9/12 (75) | 0.0739 | |
Nodal status | |||
N0 | 54/59 (92) | 0.0005 | N0 vs N2 (0.0207) |
N1 | 26/31 (84) | 0.008 | N0/N1 vs N2 (0.0316) |
N2 | 6/10 (60) | 0.3348 | |
Metastasis | |||
M0 | 86/99 (88) | 0.0014 | |
M1 | 0/1 (0) | 1.000 | |
Estrogen Receptor status | |||
ER+ | 52/56 (93) | 0.0003 | ER+ vs ER− (0.068) |
ER− | 33/42 (79) | 0.0151 | |
Progesterone Receptor status | |||
PR+ | 34/35 (97) | 0.0001 | PR+ vs PR− (0.0287) |
PR− | 51/63 (81) | 0.077 | |
HER2 receptor status | |||
HER2+ | 31/36 (86) | 0.0043 | HER2+ vs HER2− (1.0) |
HER2− | 54/62 (87) | 0.0019 | |
Age/Menopausal status | |||
<48 | 46/56 (82) | 0.0066 | |
48–54 | 23/25 (92) | 0.0019 | |
>54 | 17/19 (89) | 0.0057 |
aCalculated using Fisher’s exact test.
bP values in bold remain statistically significant at a false discovery rate (FDR) of 0.05.