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. 2018 Sep 17;8:13922. doi: 10.1038/s41598-018-32020-1

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Structural profiling of cell type specific TF networks. (a) Structural robustness was measured simulating attacks (removing high degree nodes (red)) and errors (removing randomly selected nodes). (b) Networks characterization was done measuring topological features of every network. (c) Each network was compared to random model networks by measuring its dissimilarity to an analogous ensemble of homogeneous and scale-free networks.