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. 2018 Sep 17;8:13922. doi: 10.1038/s41598-018-32020-1

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Chromatin accessibility in ESCs and adult tissue samples from Roadmap Epigenomics data²³. Number of DNase-seq tags per million reads in (a) gene promoters, (b) TF promoters, and (c) enhancers for each sample. Group mean accessibility distribution in (d) gene promoters, (e) TF promoters, and (f) enhancers. Boxplot of groups accessibility distribution entropy in (g) gene promoters, (h) TF promoters, and (i) enhancers. Horizontal lines inside violin plots correspond to the distribution median.