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. 2018 Sep 17;8:13883. doi: 10.1038/s41598-018-32306-4

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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HTR1A/B and DRD3/5 are expressed in AML and MDS. (A) HTR1A (HD n = 6; MDS n = 54; AML n = 14), (B) HTR1B (HD n = 6; MDS n = 55; AML n = 14), (C) DRD3 (HD n = 4; MDS n = 47; AML n = 14), and (D) DRD5 (HD n = 4; MDS n = 47; AML n = 14) surface expression measured by flow cytometry in blood samples from healthy donors (HD), MDS samples and AML samples. Frequency of positive cells for each marker is graphed as a box-and-whisker (turkey) plot, the statistical median is indicated as a horizontal line, error bars correspond to SEM and boxes indicated the lowest and upper quartile. **p < 0.01; ***p < 0.001; ****p < 0.0001.