Table 5.
Groups | SOD (U/mg protein) | CAT (U/mg protein) | MDA (nmol/mg protein) | GSH (μmol/g protein) | |
---|---|---|---|---|---|
Intervention groups | Control | 10.77 ± 0.16a | 141.61 ± 5.54a | 2.72 ± 0.11bc | 10.13 ± 0.46a |
Pb only | 5.95 ± 0.34b | 92.57 ± 7.22c | 4.04 ± 0.17a | 5.61 ± 0.32b | |
Pb + DSA | 10.21 ± 2.69a | 152.49 ± 14.76a | 2.20 ± 0.36c | 11.10 ± 1.37a | |
Pb + DSB | 10.71 ± 0.84a | 153.42 ± 7.90a | 2.38 ± 0.25c | 10.32 ± 0.89a | |
Pb + Excipients | 5.67 ± 0.24b | 90.02 ± 14.94c | 4.08 ± 0.44a | 5.54 ± 0.22b | |
DMSA groups | High-dose DMSA | 7.42 ± 0.46b | 124.41 ± 9.06b | 3.18 ± 0.15b | 6.77 ± 0.18b |
Low-dose DMSA | 7.16 ± 0.54b | 116.46 ± 6.73b | 3.32 ± 0.11b | 6.53 ± 0.39b | |
Therapy groups | Control | 11.04 ± 0.80a | 141.11 ± 6.79a | 2.78 ± 0.10b,c | 9.99 ± 1.01a |
Pb only | 5.48 ± 1.22b | 97.76 ± 2.77c | 4.58 ± 0.59a | 5.58 ± 0.23b | |
Pb + DSA | 9.78 ± 1.63a | 147.63 ± 8.45a | 2.39 ± 0.46c | 10.30 ± 0.81a | |
Pb + DSB | 10.39 ± 0.52a | 140.58 ± 3.12a | 2.51 ± 0.42c | 10.00 ± 0.77a | |
Pb + Excipients | 6.16 ± 0.17b | 97.68 ± 5.34c | 4.60 ± 0.50a | 5.79 ± 0.24b |
Values are for 10 mice per group. Abbreviations of group names are as in Table 2. a–cStatistically significant differences (P < 0.05) within each row comparison.