Table 1.
The characteristics of studies included in the meta-analysis.
| References | Country | Method | Outcome | Case number (High/Low) | Cut-off | Follow up time |
|---|---|---|---|---|---|---|
| Dai et al. (17) | China | Tissue Microarray, Immunohistochemistry | OS DFS | 90(28/62) | Staining scores <2 | Median time 60.8 month |
| Sideras et al. (18) | Netherlands | Tissue Microarray, Immunohistochemistry, PCR | RFS | EMC86(70/16) | 2 log likelihood | >100 months |
| AMC 60(51/9) | ||||||
| Semaan et al. (31) | Germany | Tissue microarray, Immunohistochemistry | OS | 176(88/88) | Median | 60 months |
| Xie et al. (32) | China | Immunohistochemistry | OS DFS | 167(24/143) | Membranous staining = 5% of tumor cells | 150 months |
| Chen et al. (16) | China | Immunohistochemistry | OS RFS | 231(58/173) | Membranous staining percentage = 5% | >5 years |
| Jung et al. (30) | Korea | Immunohistochemistry | OS DFS | 85(23/62) | Staining scores = 3 | 125 months |
| Umemoto et al. (33) | Japan | Immunohistochemistry | OS RFS | 80(37/43) | Staining score = 1 | median time 2,427 days |
| Zeng et al. (34) | China | Immunohistochemistry | OS DFS | 156(88/68) | Staining score = 1 | 40 months |
| Gao et al. (6) | China | Tissue microarray, Immunohistochemistry | OS RFS DFS | 240(60/180) | The 75th percentile | 120 months |
| Gabrielson et al. (35) | America | Immunohistochemistry, semi-quantitative analysis | OS RFS | 58(19/39) | NA | meantime 39.7 months |
| Kan et al. (36) | China | Immunohistochemical Staining | OS | 128(105/23) | 1 point | median time 10 months |
| Wu et al. (4) | China | Immunohistochemistry | OS | 71(35/36) | The median value of B7-H1+cell density in tumor tissues on IHC | 80 months |
| Finkelmeier et al. (37) | Germany | ELISA | OS | 215(64/151) | 0.8 ng/ml | 298 ± 304 days with a range of 1–1464 days |