Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Aug 17;145(17):dev166801. doi: 10.1242/dev.166801

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2018. Published by The Company of Biologists Ltd

PMC Copyright notice

Fig. 8. — A mesodermal fate map for adipose tissue. (A) Schematic showing the mesodermal fate map for adipose tissue based on tracing with Meox1-Cre:mTmG, Pax7-Cre:mTmG and HoxB6-Cre:mTmG systems. Red, somitic mesoderm and derivative adipocyte lineages; yellow, central dermomyotome and derivative adipocyte lineages; blue, posterior lateral plate mesoderm and derivative adipocyte lineages. (B) Schematic showing a model fate map for interscapular adipocyte lineages based on Pax7-Cre:mTmG tracing in this study and Pax3/Myf5-Cre:mTmG tracing by Sanchez-Gurmaches and Guertin (2014). It is proposed that a subset of Pax3⁺ progenitors in the epaxial dermomyotome and Pax7/Pax3⁺ progenitors in the central dermomyotome are fated to the interscapular adipocyte lineage. These Pax3⁺ or Pax7/Pax3⁺ cells acquire Myf5 expression in a Pax3-dependent manner (Sato et al., 2010) and go on to establish interscapular white and brown adipocytes. (C) Schematic of somite subcompartments. (D) Model lineage hierarchy for interscapular adipocytes based on Pax7-Cre:mTmG tracing in this study and Pax3/Myf5-Cre:mTmG tracing by Sanchez-Gurmaches and Guertin (2014).