Table II.
List of miRNAs with altered expression, on saliva specimen testing, in oral and/or oropharyngeal cancers.
| Name | Status | Tumor type | (Refs.) |
|---|---|---|---|
| miR-9 | Overexpressed | HPV-negative HNSCC | (62) |
| miR-24 | Overexpressed | OSCC (vs. healthy controls) | (62,108) |
| miR-27b | Overexpressed | OSCC (vs. healthy controls) OSCC in remission | (62,108) |
| miR-31 | Overexpressed | HPV-related OSCC and OPSCC (vs. healthy controls and leukoplakia) | (62,109,110) |
| miR-134 | Overexpressed | HNSCC | (62,111) |
| miR-191 | Overexpressed | HNSCC | (62,111) |
| miR-125a | Underexpressed | OSCC | (62,112) |
| miR-136 | Underexpressed | OSCC (vs. healthy controls) | (62,108) |
| miR-147 | Underexpressed | OSCC (vs. healthy controls) | (62,108) |
| miR-148a | Underexpressed | OSCC (vs. healthy controls) | (62,108) |
| miR-200a | Underexpressed | OSCC (vs. control samples) | (62,112,113) |
| miR-222 | Underexpressed | OSCC and OPSCC | (62,109) |
| miR-323-5p | Underexpressed | OSCC (vs. healthy controls) | (62,108) |
| miR-503 | Underexpressed | OSCC (vs. healthy controls) | (62,108) |
| miR-622 | Underexpressed | OSCC (vs. healthy controls) | (62,108) |
| miR-646 | Underexpressed | OSCC (vs. healthy controls) | (62,108) |
| miR-668 | Underexpressed | OSCC (vs. healthy controls) | (62,108) |
| miR-877 | Underexpressed | OSCC (vs. healthy controls) | (62,108) |
| miR-1250 | Underexpressed | OSCC (vs. healthy controls) | (62,108) |
miRNA/miR, microRNA; OSCC, oral squamous cell carcinoma; OPSCC, oropharyngeal squamous cell carcinoma; HNSCC, head and neck squamous cell carcinoma; HPV, human papillomavirus.