Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Jun 14;17(3):928–940. doi: 10.1177/1534735418781725

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2018

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

PMC Copyright notice

Figure 3. — (A) Salivary cortisol, (B) salivary α-amylase, (C-F) pro-inflammatory cytokines, (G and H) anti-inflammatory cytokines, and (I) matrix metalloproteinase-9 trajectories in children and adolescents with osteosarcoma on clown intervention (N = 6). The graphs show the biomarkers trajectories per patient at preintervention (baseline/day 1) and at postintervention (day 3). Pediatric patients with metastatic osteosarcoma are represented in the graph by dashed lines. Full lines show pediatric patients with nonmetastatic osteosarcoma. Samples were collected +1, +4, +9, and +13 hours post-awakening (8:30 am), that is, at 9:30 am, 12:30 pm, 5:30 pm, and 9:30 pm, respectively.