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. 2018 Jun 11;155(2):263–272. doi: 10.1111/imm.12949

Table 1.

Associations among tumour tissue phosphatase and tensin homologue (PTEN), Yes‐associated protein 1 (YAP1) and CD33 levels and the clinical parameters of patients with colorectal cancer in 2005

Clinicopathological parameter High level of CD33 (%) P value High level of YAP1 (%) P value High level of PTEN (%) P value
Age 0·788 0·263 0·860
< 60 years 43 (64·1) 23 (33·3) 34 (51·5)
≥ 60 years 44 (62·0) 31 (42·5) 35 (50·0)
Gender 0·576 0·264 0·014 a
Female 35 (60·3) 20 (32·8) 36 (63·2)
Male 52 (65·0) 34 (42·0) 33 (41·8)
Duke stage 0·027 a 0·001 a 0·023 a
A–B 31 (52·5) 13 (22·0) 36 (62·1)
C–D 56 (70·9) 41 (49·4) 33 (42·3)
Histological grade 0·010 a 0·001 a 0·005 a
Well‐moderate 51 (56·0) 27 (29·0) 52 (59·8)
Poor 34 (79·1) 25 (58·1) 15 (34·1)
Metastasis 0·000 a 0·000 a 0·124
Yes 57 (87·7) 38 (55·9) 29 (43·9)
No 30 (41·1) 16 (21·6) 40 (57·1)
a

P < 0·05, as determined by the Pearson χ2 test. High/low PTEN, YAP1, and CD33 values are based on the median density value.