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. 2018 Sep 17;18:896. doi: 10.1186/s12885-018-4801-z

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Levels of MiR-126 in tissues and serum of studied populations and its biomarker performance. Box-plots showing MiR-126 levels in biopsies of normal mucosa (M), Intestinal-type adenocarcinomas (ITACs), sinonasal inverted papillomas (SIPs) and nasal inflammatory polyps (NIPs) shown as relative expression (2^-∆Ct) (a) or fold-change (b). c Relative expression of MiR-126 in serum of patients with ITACs and in healthy controls. d Receiver-operating curve (ROC) of serum MiR-126 to differentiate between ITAC patients and control subjects. MiR-126 yielded an AUC of 0.813 ± 0.064 with 80% sensitivity and 70% specificity in discriminating patients with SNC from healthy subjects, p < 0.0005. *Mucosa versus ITAC, SIP, and NIP groups, p < 0.05