Table 3.
Groups | Group I (Control) |
Group II (TAU-CL) |
Group III (AZA) |
Group IV (TAU-CL/AZA) |
---|---|---|---|---|
Parameters | ||||
DNA fragmentation (%) | 68.2 ± 5.01 | 70.55± 6 | 91.59a ± 10.59 | 68.19b ± 4.8 |
Caspase-9 activity (ng/g tissue) |
1.6 ± 0.15 | 1.7 ± 0.07 | 2.5a ± 0.13 | 1.6b ± 0.17 |
BCL2 (ng/mg tissue) |
1.25 ± 0.02 | 1.3 ± 0.08 | 0.75a ± 0.05 | 1.2b ± 0.13 |
The percentage of DNA fragmentation, Caspase 9 activity, and Bcl-2 expression, measured by western blot, β-actin was used as a loading control (C), in different groups
Data are expressed as the mean ± SEM, and data were analyzed using one-way ANOVA followed by the Bonferroni post hoc multiple comparison test (n = 10). Difference between groups were considered statistically significant at P ≤ 0.05. (a) Significant values versus the group control, (b) Significant values versus the AZA group