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. 2018 Sep 17;12:44. doi: 10.1186/s40246-018-0176-0

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Conservation and distribution of TBX2 and TBX3 variants. a, b Alignments of TBX2 and TBX3 protein among different species. All variants were highly conserved in vertebrates. c, d Diagram of the TBX2 and TBX3 gene exons and protein with location of variants identified in this study