Table 3.
Summary of recommendations for newly diagnosed NLPHL
Stage | Treatment |
---|---|
Stage IA | 30-Gy IS-RT alone |
Early stages except for stage IA | 2 × (R-)ABVD + 20-Gy IS-RT |
Intermediate stages | 4 × (R-)ABVD + 30-Gy IF-RT |
Advanced stages | 6 × R-CHOP ± localized RT at 30 Gy |
ABVD, doxorubicin, bleomycin, vinblastine, dacarbazine; IF-RT, involved-field radiotherapy; IS-RT, involved-site radiotherapy; NLPHL, nodular lymphocyte-predominant Hodgkin lymphoma; R, rituximab; R-CHOP, rituximab, cyclophosphamide, doxorubicin, vincristine, prednisone; RT, radiotherapy.