Treatment options for consolidation and prolonged or continuous therapy based on results of randomized trials. KRd has not been tested in randomized comparisons. Improved PFS was seen in (1) 3 of 3, (2) 1 of 2, (3) 1 of 1, (4) 1 of 4, (5) 4 of 4, and (6) 6 of 6 randomized trials. TXT, treatment; BTZ, bortezomib; VCD, Velcade-cyclophosphamide-dexamethasone; THAL, thalidomide; REV, Revlimid; DEX, dexamethasone.