Fig. 2.

Changes in transcript abundance of genes involved in central metabolic pathways and antioxidant system when Schizochytrium sp. HX-308 was cultured with high oxygen supply condition. a Transcriptional regulation of the central carbon metabolic pathways, including glycolysis, pentose phosphate pathway, and tricarboxylic acid cycle. b Transcriptional regulation of the antioxidant defense system. Key enzymes are included in the map and presented as their names. Gene fold changes as indicated by color boxes. Glycolysis; PPP, pentose phosphate pathway; G6PD, glucose-6-phosphate dehydrogenase; 6PGD, 6-phosphogluconate dehydrogenase; EMP, Embden–Meyerhof–Parnas pathway; HK, hexokinase; PFK, phosphofructokinase; FBA, fructose-bisphosphate aldolase; PYC, pyruvate carboxylase; PK, pyruvate kinase; TCA, tricarboxylic acid; CS, citrate synthase; MDH, malate dehydrogenase; FUM, fumarate hydratase; IDH, isocitrate dehydrogenase; ME, malic enzyme; ACL, citrate lyase; KGDC, 2-oxoglutarate dehydrogenase; SDH, succinate dehydrogenase; SOD, superoxide dismutase; CAT, catalase; APX, ascorbate peroxidase; ROS, reactive oxygen species; GSH-Px, glutathione peroxidase