Skip to main content
. 2018 Feb 26;35(5):589–594. doi: 10.1093/fampra/cmy001

Table 1.

List of high-risk medications for patients with stage III/IV chronic kidney disease

Tier 1: relatively contraindicated: NSAIDs Tier 2: relatively contraindicated: other Tier 3: needs dose adjustment
Diclofenac Acarbose Benazepril
Diflunisal Chlorpropamide Captopril
Etodolac Glyburide Lisinopril
Fenoprofen calcium Nitrofurantoin Ramipril
Flurbiprofen Acebutolol
Floctafenine Atenolol
Ibuprofen Bisoprolol
Indomethacin Amiloride
Ketoprofen Metformin
Ketorolac tromethamine Fluconazole
Meclofenamate sodium Imipenem/Cilastatin
Mefenamic acid Cefixime
Meloxicam Cefprozil
Nabumetone Ceftibuten
Naproxen Ciprofloxacin
Oxaprozin Ofloxacin
Piroxicam Allopurinol
Celecoxib Famotidine
Sulindac Metoclopram
Tiaprofenic acid Ranitidine
Tolmetin

NSAID, non-steroidal anti-inflammatory drug.