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. 2018 Sep 11;9:1259. doi: 10.3389/fphys.2018.01259

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Copyright © 2018 Ahmad Bakir, Al Abed, Stevens, Lovell and Dokos.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Electrical activation in the standard model following initiation at t = 2,002 ms. It should be noted that the recovery spreads in the opposite direction of activation. (B) Electrical activation time map in the standard model. Comparison of (C) LV free wall myocardium endocardial and epicardial, (D) Purkinje fiber, and (E) Purkinje-myocyte junction action potential profiles. (F) Active stress profile of the myocardium taken at the same location as (C). The time derivative of membrane potential of the (G) Purkinje fiber and (H) Purkinje-myocyte junction, taken at the same locations as in (D,E).