Table 2.
Published studies on occupational transmission of N meningitidis in the healthcare settings (N/A=data not available; PPE=personal protective equipment; PEC=post-exposure chemoprophylaxis)
| Author(s) | Country | Year | Patient(s) | No. of cases | Serogroup | Respiratory use of PPE reported | Source of infection | PEC | Incubation (days) | Prognosis |
| Feldman HA, 1972 (30) | USA | N/A | Medical staff | 4 | N/A | N/A | Mouth-to-mouth resuscitation | N/A | N/A | N/A |
| CDC, 1978(26) | USA | 1978 | Nurse | 1 | B | NO | Patient; emergency room evaluation | YES | 3 | N/A |
| Gehanno JF et al. 1999(15) | France | 1999 | Physician | I | C | NO | Patient; intubation procedures; delivery of oxygen; | NO | 7 | Recovered without sequelae |
| Gilmore A, et al. 2000 (20) | United Kingdom | 1986 | Physician | 1 | B | NO | Patient; full clinical examination; patient coughed into doctor face; daily contact thereafter. | NO | 4 | N/A |
| 1987 | Paramedic crew | 1 | C | NO | Patient; control of airways; delivery of oxygen; | NO | 7 | N/A | ||
| 1996 | Nurse | 1 | B | NO | Patient; interaction with patient who coughed and cried; | NO | 5 | N/A | ||
| Petsas A et al. 2008 (28) | United Kingdom | 2007 | Paramedic crew (Ambulance worker) | 1 | B | NO | Patient; control of airways; delivery of oxygen; | NO | 4 | Recovered without sequelae |
| CDC, 2010(27) | USA | 2009 | Respiratory therapist | 1 | C | NO | Patient; intubation procedures | NO | 5 | Recovered without sequelae |
| Puleston R et al. 2012(29) | United Kingdom | 2012 | Paramedic crew (Ambulance worker) | 1 | W135 | N/A | Involved in two community cases but impossible to determine whether paramedic was a primary or a secondary case | YES | 16 | Recovered without sequelae |
| Total | Paramedic crew = 4 (33.3%) Physicians = 2(16.7%) Nurse = 2 (16.7%) Respiratory therapist = 1 (8.3%) Medical staff (undefined) = 4 (33.3%) |
12 | B =4 (33.3%) C = 3 (25.0%) W135 = 1 (8.3%) N/A = 4 (33.3%) |
NO = 7 (58.3%) N/A = 5 (41.7%) |
Patients = 100% Airway management / resuscitation maneuvers = 10 (83.3%) Other interactions = 3 (25.0%) | NO = 6 (50.0%) YES = 2 (16.7%) N/A = 4 (33.3%) |
Median: 5 days Range: 3-16 |
Recovered without sequelae = 4 (33.3%) N/A = 8 (66.7%) |