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. 2018 May 14;75(8):1–10. doi: 10.1001/jamaneurol.2018.0963

Figure 2. Functional Deficits in Childhood Cancer Survivors (CCS).

Figure 2.

A, Functional assessments using the Movement Assessment Battery for Children (MABC) in child and adolescent CCS exposed to neurotoxic chemotherapy compared with population reference ranges. Functional deficit is seen in 2 of 3 manual dexterity tasks and 1 of 3 balance tasks and is represented as the number of standard deviations below the population mean. The dotted line indicates the population mean and the error bars, SEM. B-D, Functional assessments in adult CCS exposed to neurotoxic chemotherapy compared with laboratory controls. B, Fingertip sensory threshold for light touch using Von Frey monofilaments (increased threshold in CCS, 0.1 mN; 95% CI, 0.03-0.2; P = .01). C, Fingertip cutaneous resolution threshold using the grating orientation task (increased threshold in CCS, 0.7 mm; 95% CI, 0.1-1.2; P = .003). D, Manual dexterity using the grooved peg board task (increased time to completion in CCS, 5.9 s; 95% CI, 1.6-10.1; P = .008). The black bar indicates the median and the error bars, interquartile ranges.