Table 3. Gene-Based Analysis of Rare Variants on Response to Anti–Vascular Endothelial Growth Factor Therapy in Neovascular Age-Related Macular Degeneration.
Gene | Chromosome | Chromosomal Positiona | No. of Rare Variants | RAC | P Value |
---|---|---|---|---|---|
C10orf88 | 10 | 124 692 082 to 124 712 511 | 3 | 7 | 4.22 × 10−7 |
UNC93B1 | 11 | 67 765 163 to 67 770 499 | 2 | 14 | 6.09 × 10−7 |
Abbreviation: RAC, rare allele count.
Chromosome and chromosomal position according to the NCBI RefSeq hg19 human genome reference assembly.