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. 2018 Jul 12;144(8):712–717. doi: 10.1001/jamaoto.2018.0939

Table 2. Crude and Adjusted HRs for Combined Cochlear Disorders.

Variable Crude HR (95% CI) Adjusted HR (95% CI)a
Migraine (yes or no) 2.83 (2.01-3.99) 2.71 (1.86-3.93)
Sex (men or women) 1.18 (0.83-1.67) 0.93 (0.64-1.34)
Age (per year) 1.03 (1.02-1.04) 1.02 (1.01-1.04)
Comorbidity (yes or no)
Sleep disorders 1.01 (0.44-2.29) 1.20 (0.52-2.75)
Heart diseases 1.42 (0.72-2.80) 1.12 (0.53-2.37)
Hypertension 1.45 (0.78-2.70) 0.71 (0.35-1.45)
Diabetes 4.74 (2.61-8.59) 3.70 (1.93-7.06)
Hyperlipidemiab NA NA
Chronic kidney disease 2.59 (0.36-18.55) 1.56 (0.21-11.88)
Chronic hepatitis 2.01 (0.81-4.98) 1.21 (0.46-3.20)
Anxiety 1.91 (0.84-4.37) 1.86 (0.81-4.30)
Depression 0.81 (0.11-5.80) 0.55 (0.08-3.98)
COPD 1.69 (0.97-2.96) 1.78 (1.01-3.15)
Pregnancyb NA NA
Menopause 6.58 (0.92-47.11) 4.62 (0.63-33.90)
Oral contraceptives 1.95 (0.62-6.12) 1.86 (0.58-6.02)
Geographic region
Northern 1 [Reference] 1 [Reference]
Central 1.11 (0.71-1.73) 1.06 (0.64-1.75)
Eastern 0.69 (0.17-2.82) 0.59 (0.14-2.50)
Southern 1.34 (0.91-2.00) 1.20 (0.78-1.85)
Urbanization level
Urban 1 [Reference] 1 [Reference]
Suburban 0.76 (0.51-1.13) 0.78 (0.51-1.17)
Rural 1.04 (0.67-1.62) 1.04 (0.61-1.77)
Enrollee category
1 1 [Reference] 1 [Reference]
2 0.28 (0.12-0.66) 0.40 (0.17-0.95)
3 1.87 (1.22-2.87) 1.29 (0.81-2.05)
4 1.30 (0.86-1.95) 1.29 (0.83-2.00)

Abbreviations: COPD, chronic obstructive pulmonary disease; HR, hazard ratio; NA, not applicable.

a

Adjusted for all covariates (age per year, sex, comorbidity, use of oral contraceptives, geographic region, urbanization level, and enrollee category).

b

Correlated with another independent factor during regression analysis.