Table 2. Univariate Analysis of Dermoscopic Variables Associated With SMIS vs Benign LM in 45 South Korean Patients.
| Dermoscopic Variable | No. (%) | Sensitivity for SMIS | Specificity for SMIS | Overall Accuracy | OR (95% CI) | P Value | |
|---|---|---|---|---|---|---|---|
| SMIS (n = 19) | Benign LM (n = 26) | ||||||
| Width of pigmentation, mean (SD), mm | 9.03 (3.96) | 3.94 (3.07) | .001 | ||||
| ≥3 | 17 (89) | 16 (62) | 0.90 | 0.38 | 0.60 | 5.31 (1.01-28.07)a | .05 |
| ≥6 | 16 (84) | 4 (15) | 0.84 | 0.85 | 0.84 | 29.33 (5.75-149.65)a | <.001 |
| Pigmentation | |||||||
| Multicolor | 17 (89) | 11 (42) | 0.90 | 0.58 | 0.71 | 11.59 (2.21-60.89)a | .004 |
| Unicolor | 2 (11) | 15 (58) | 0.11 | 0.42 | 0.29 | 0.09 (0.02-0.45)a | |
| Pattern | |||||||
| Asymmetry | 18 (95) | 9 (35) | 0.95 | 0.65 | 0.78 | 34.00 (3.88-297.70)a | .001 |
| Border fading | 14 (74) | 6 (23) | 0.74 | 0.77 | 0.76 | 9.33 (2.37-36.70)a | .001 |
| Triangular pattern | 4 (21) | 1 (4) | 0.21 | 0.96 | 0.64 | 6.67 (0.68-65.37) | .10 |
| Dots or globules | 2 (11) | 1 (4) | 0.11 | 0.96 | 0.60 | 2.94 (0.25-35.06) | .39 |
| Hutchinson signb | 8 (42) | 1 (4) | 0.42 | 0.96 | 0.73 | 18.18 (2.02-163.52)a | .01 |
| Nail plate dystrophy | 4 (21) | 2 (8) | 0.21 | 0.92 | 0.62 | 3.20 (0.52-19.67) | .21 |
Abbreviations: LM, longitudinal melanonychia; OR, odds ratio; SMIS, subungual melanoma in situ.
a
Indicates ORs that are significantly different.
b
Defined as periungual pigmentation of the nail fold or hyponychium.