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. 2018 Jul 2;172(9):867–875. doi: 10.1001/jamapediatrics.2018.1811

Table 2. In-Hospital Mortality and Morbidity of Very Preterm Infants of Mothers With Diabetes.

Characteristic No. (%) OR (95% CI)
Infants of Mothers With Diabetes
(n = 3280)
Infants of Mothers Without Diabetes
(n = 73 080)
Crude Model 1
Adjusteda
Model 2
Adjustedb
Model 3
PS-Matchedc
In-hospital mortality 215 (6.6) 6043 (8.3) 0.78 (0.68-0.90) 1.06 (0.90-1.24) 1.16 (0.97-1.39) 1.08 (0.88-1.32)
In-hospital mortality or severe neonatal morbidityd 984 (31.6) 28 803 (40.6) 0.67 (0.62-0.73) 0.94 (0.86-1.03) 0.99 (0.88-1.10) 0.94 (0.85-1.04)
RDS 2165 (67.0) 45 237 (62.4) 1.22 (1.13-1.32) 1.04 (0.96-1.13) 1.01 (0.91-1.11) 1.05 (0.95-1.17)
IVH grade 3-4 or cPVL 218 (6.9) 6187 (8.7) 0.78 (0.68-0.90) 0.84 (0.72-0.98) 0.91 (0.77-1.08) 0.91 (0.75-1.12)
Treated PDA 766 (23.4) 18 536 (25.4) 0.90 (0.83-0.97) 1.00 (0.91-1.10) 0.98 (0.89-1.09) 1.01 (0.91-1.13)
Severe ROP (treated) 157 (4.8) 5259 (7.2) 0.82 (0.70-0.96) 0.93 (0.77-1.11) 0.85 (0.69-1.03) 1.01 (0.81-1.26)
BPD 611 (20.3) 18 544 (27.9) 0.66 (0.60-0.72) 0.96 (0.87-1.07) 1.01 (0.89-1.14) 0.94 (0.83-1.06)
NECe 137 (5.2) 1940 (4.2) 1.25 (1.04-1.49) 1.18 (0.97-1.43) 1.18 (0.97-1.44) 1.10 (0.84-1.43)

Abbreviations: BPD, bronchopulmonary dysplasia; cPVL, cystic periventricular leukomalacia; IVH, intraventricular hemorrhage; N, total number in category; n, number in group; NEC, necrotizing enterocolitis; OR, odds ratio; PDA, patent ductus arteriosus; PS, propensity score; RDS, respiratory distress syndrome; ROP, retinopathy of prematurity.

a

Model 1 adjusted for maternal age of 35 years or older, maternal hypertensive disease in pregnancy, gestational age, sex, birth weight z score, and network.

b

Model 2 adjusted for the same covariates as in model 1 and antenatal corticosteroids, mode of delivery, and outborn.

c

Model 3: PS-matched ORs, stratified by network.

d

Severe neonatal morbidity defined as IVH grade 3-4, cPVL, treated ROP, or BPD.

e

UK info unavailable.