Table 3. Mortality and Composite Outcome of Infants Born to Mothers With or Without Diabetes by Gestational Age.
| Gestational Age, wk | No. (%) | OR (95% CI) | ||
|---|---|---|---|---|
| Infants of Mothers With Diabetes | Infants of Mothers Without Diabetes | Crude | Adjusteda | |
| In-hospital mortality | ||||
| 24 | 42/162 (25.9) | 1760/6171 (28.5) | 0.88 (0.61-1.25) | 1.10 (0.70-1.71) |
| 25 | 35/209 (16.8) | 1294/7347 (17.6) | 0.94 (0.65-1.36) | 1.07 (0.69-1.68) |
| 26 | 47/336 (14.0) | 984/8817 (11.2) | 1.29 (0.94-1.77) | 1.65 (1.13-2.40) |
| 27 | 31/428 (7.2) | 799/10 083 (7.9) | 0.91 (0.63-1.32) | 0.87 (0.54-1.40) |
| 28 | 29/528 (5.5) | 556/11 684 (4.8) | 1.16 (0.79-1.71) | 1.52 (0.92-2.50) |
| 29 | 14/614 (2.3) | 353/11 605 (3.0) | 0.74 (0.43-1.28) | 1.05 (0.55-1.98) |
| 30 | 9/578 (1.6) | 190/10 072 (1.9) | 0.82 (0.42-1.61) | 0.51 (0.16-1.66) |
| 31 | 8/425 (1.9) | 107/7301 (1.5) | 1.29 (0.62-2.66) | 1.92 (0.79-4.67) |
| Composite outcome, in-hospital mortality or severe neonatal morbidityb | ||||
| 24 | 130/159 (81.8) | 5103/6090 (83.8) | 0.87 (0.58-1.30) | 1.13 (0.68-1.88) |
| 25 | 141/203 (69.5) | 5235/7165 (73.1) | 0.84 (0.62-1.14) | 0.85 (0.61-1.19) |
| 26 | 185/325 (56.9) | 5170/8575 (60.3) | 0.87 (0.70-1.09) | 1.08 (0.83-1.41) |
| 27 | 171/413 (41.4) | 4550/9815 (46.4) | 0.82 (0.67-1.00) | 1.03 (0.80-1.33) |
| 28 | 149/503 (29.6) | 3905/11 364 (34.4) | 0.80 (0.66-0.98) | 0.99 (0.77-1.26) |
| 29 | 107/581 (18.4) | 2670/11 208 (23.8) | 0.72 (0.58-0.89) | 0.89 (0.68-1.18) |
| 30 | 61/541 (11.3) | 1434/9704 (14.8) | 0.73 (0.56-0.96) | 0.75 (0.51-1.09) |
| 31 | 40/394 (10.2) | 736/7024 (10.5) | 0.97 (0.69-1.35) | 1.59 (1.05-2.42) |
Abbreviation: OR, odds ratio.
a
Adjusted for the following: a maternal age of 35 years or older, maternal hypertensive disease in pregnancy, antenatal corticosteroids, mode of delivery, gestational age, sex, outborn-birth weight z score, and network.
b
Severe neonatal morbidity defined as intraventricular hemorrhage grade 3-4, cystic periventricular leukomalacia, retinopathy of prematurity stage ≥3, or bronchopulmonary dysplasia.