Table 4. Composite Outcome of Very Preterm Infants Born to Mothers With Diabetes by Neonatal Network.
| Neonatal Network | No./Total No. (%) | OR (95% CI) | ||
|---|---|---|---|---|
| Infants of Mothers With Diabetes | Infants of Mothers Without Diabetes | Crude | Adjustedb | |
| CNN | 316/1130 (28.0) | 4203/11 305 (37.2) | 0.66 (0.57-0.75) | 0.96 (0.80-1.14) |
| FinMBR | 66/190 (34.7) | 493/1385 (35.6) | 0.96 (0.70-1.32) | 1.17 (0.79-1.74) |
| INN | 70/295 (23.7) | 1855/5452 (34.0) | 0.60 (0.46-0.79) | 0.82 (0.60-1.14) |
| NRNJ | 269/697 (38.6) | 8245/21 512 (38.3) | 1.01 (0.87-1.18) | 1.07 (0.89-1.29) |
| SNQ | 21/65 (32.3) | 1247/3525 (35.4) | 0.87 (0.52-1.47) | 1.31 (0.72-2.38) |
| TuscanNN | 23/101 (22.8) | 240/831 (28.9) | 0.73 (0.45-1.18) | 0.94 (0.52-1.71) |
| UKNC | 219/641 (34.2) | 12 520/26 935 (46.5) | 0.60 (0.51-0.70) | 0.85 (0.70-1.04) |
| All networks | 984/3280 (31.6) | 28 803/73 080 (40.6) | 0.67 (0.62-0.73) | 0.99 (0.88-1.10) |
Abbreviations: BPD, bronchopulmonary dysplasia; CNN, Canadian Neonatal Network; FinMBR, Finnish Medical Birth Registry; INN, Israel Neonatal Network; NRNJ, Neonatal Research Network of Japan; OR, odds ratio; SNQ, Swedish Neonatal Quality Register; TuscanNN, Tuscany Neonatal Network (Italy); UKNC, UK Neonatal Collaborative.
a
In-hospital mortality or severe neonatal morbidity defined as intraventricular hemorrhage grade 3-4, cystic periventricular leukomalacia, -retinopathy of prematurity stage ≥3, or BPD.
b
Adjusted for a maternal age of 35 years or older, maternal hypertensive disease in pregnancy, antenatal corticosteroids, mode of delivery, gestational age, sex, outborn, and birth weight z score.