Table 1. Study Variables by First-Time Antidepressant Use.
| Variable | No. of Women With First Redeemed Antidepressant Prescription (n = 59 465) | Woman-Years at Risk of First Redeemed Antidepressant Prescription (n = 2 502 659) | Unadjusted Rate of New Redeemed Antidepressant Prescriptions per 1000 Woman-Years at Risk (95% CI) |
|---|---|---|---|
| Abortion | |||
| No abortion | 52 475 | 2 336 237 | 22.5 (22.3-22.7) |
| Year before abortion | 1285 | 28 115 | 45.7 (43.3-48 .3) |
| Year after abortion | 1372 | 27 653 | 49.6 (47.1-52.3) |
| >1-5 y After abortion | 2986 | 73 767 | 40.5 (39.1-42.0) |
| >5 y After abortion | 1347 | 36 887 | 36.5 (34.6-38.5) |
| Childbirth | |||
| No childbirth | 48 176 | 2 132 471 | 22.6 (22.4-22.8) |
| Year before childbirth | 814 | 73 569 | 11.1 (10.3-11.9) |
| Year after childbirth | 1436 | 65 090 | 22.1 (21.0-23.2) |
| >1-5 y After childbirth | 6459 | 179 585 | 36.0 (35.1-36.9) |
| >5 y After childbirth | 2580 | 51 944 | 49.7 (47.8-51.6) |
| History of psychiatric contact | |||
| No | 45 616 | 2 374 605 | 19.2 (19.0-19.4) |
| Yes | 13 849 | 128 054 | 108.2 (106.4-110.0) |
| History of receiving antianxiety medication | |||
| No | 48 853 | 1 386 075 | 20.5 (20.3-20.7) |
| Yes | 10 612 | 116 584 | 91.0 (89.3-92.8) |
| History of receiving antipsychotic medication | |||
| No | 56 448 | 2 486 341 | 22.7 (22.5-22.9) |
| Yes | 3017 | 16 318 | 184.9 (178.4-191.6) |
| Maternal history of psychiatric contact | |||
| No | 50 940 | 2 291 742 | 22.2 (22.0-22.4) |
| Yes | 8525 | 210 916 | 40.4 (39.6-41.3) |
| Paternal history of psychiatric contact | |||
| No | 52 242 | 2 317 045 | 22.6 (22.4-22.7) |
| Yes | 7223 | 185 614 | 38.9 (38.0-39.8) |
| Charlson Comorbidity Indexa | |||
| 0 | 53 309 | 2 329 096 | 22.9 (22.7-23.1) |
| 1 | 4832 | 137 674 | 35.1 (34.1-36.1) |
| ≥2 | 1324 | 35 888 | 36.9 (35.0-38.9) |
a
Scoring for the Charlson Comorbidity Index is explained in the Variables and Covariates subsection of the Measures subsection of the Methods section.