Table 2. Adjusted Incident Rate Ratios (95% CI) of Antidepressant Use by Time Relative to First Abortion and First Childbirth.

Variable	Basic Modela	Fully Adjusted Modelb
Abortion
No abortionc	1 [Reference]	1 [Reference]
Year before abortion	1.83 (1.73-1.93)	1.46 (1.38-1.54)
Year after abortion	1.97 (1.87-2.08)	1.54 (1.45-1.62)
>1-5 y After abortion	1.61 (1.55-1.67)	1.24 (1.19-1.29)
>5 y After abortion	1.47 (1.39-1.56)	1.12 (1.05-1.18)
Childbirth
No childbirthc	1 [Reference]	1 [Reference]
Year before childbirth	0.52 (0.49-0.56)	0.47 (0.43-0.50)
Year after childbirth	1.06 (1.01-1.12)	0.93 (0.88-0.98)
>1-5 y After childbirth	1.82 (1.77-1.87)	1.52 (1.47-1.56)
>5 y After childbirth	2.81 (2.68-2.94)	1.99 (1.91-2.09)
History of psychiatric contact
No		1 [Reference]
Yes		3.70 (3.62-3.78)
History of receiving antianxiety medication
No		1 [Reference]
Yes		3.03 (2.96-3.10)
History of receiving antipsychotic medication
No		1 [Reference]
Yes		1.88 (1.81-1.96)
Maternal history of psychiatric contact
No		1 [Reference]
Yes		1.21 (1.18-1.24)
Paternal history of psychiatric contact
No		1 [Reference]
Yes		1.25 (1.22-1.29)
Charlson Comorbidity Indexd
0		1 [Reference]
1		1.24 (1.21-1.28)
≥2		1.17 (1.11-1.24)

^aModel includes abortion, childbirth, age, and cohort (calendar year).

^bModel includes abortion, childbirth, age, cohort (calendar year), history of psychiatric contact, history of receiving antianxiety medication, history of receiving antipsychotic medication, maternal and paternal history of psychiatric illness, and mother’s and father’s educational level when the woman was 15 years old.

^cExcluding the year before the first childbirth or abortion.

^dScoring for the Charlson Comorbidity Index is explained in the Variables and Covariates subsection of the Measures subsection of the Methods section.