Table 2. Disability 6 Months After Neurologic Illness Onset Among Patients With Guillain-Barré Syndrome With vs Without Evidence of Zika Virus Infection, Puerto Rico, 2016.
| Variable | With Evidence of Zika Virus Infection (n = 60) |
Without Evidence of Zika Virus Infection (n = 27) |
P Value |
|---|---|---|---|
| Facial Disability Indexa | |||
| Median score (range) | 95 (25-100) | 100 (55-100) | .13 |
| Disability, No./Total No. (%) | |||
| Brushing teeth | 8/56 (14.3) | 3/23 (13.0) | >.99 |
| Excessive or inadequate tearing | 30/56 (53.6) | 6/23 (26.1) | .03 |
| Speaking | 15/56 (26.8) | 3/23 (13.0) | .19 |
| Difficulty drinking from a cup | 10/56 (17.9) | 0/23 | .03 |
| Chewing food | 12/56 (21.4) | 1/23 (4.3) | .09 |
| Overall disability sum scorea | |||
| Median score (range) | 3 (0-12) | 3 (0-12) | .95 |
| Disability, No./Total No. (%) | |||
| Washing hair | 16/56 (28.6) | 5/23 (21.7) | .53 |
| Turning keys | 14/56 (25.0) | 5/23 (21.7) | .76 |
| Using utensils | 14/56 (25.0) | 6/23 (26.1) | .92 |
| Using buttons | 15/56 (26.8) | 7/23 (30.4) | .74 |
| Dressing | 17/56 (30.4) | 4/23 (17.4) | .24 |
| Any difficulty walking | 27/56 (48.2) | 12/23 (52.2) | .75 |
| Able to walk 10 m without an aid | 32/56 (57.1) | 16/23 (69.6) | .30 |
| Need support to walk 10 m | |||
| Need 1 crutch to walk 10 m | 9/56 (16.1) | 2/23 (8.7) | .64 |
| Need 2 crutches to walk 10 m | 7/56 (12.5) | 1/23 (4.3) | |
| Need wheelchair to walk 10 m | 8/56 (14.3) | 4/23 (17.4) | |
| For those needing wheelchair, can stand and walk 1 m with help | 6/8 (75.0) | 0/4 | .06 |
| For those needing wheelchair, can make purposeful movement with legs | 8/8 (100) | 4/4 (100) | |
| Modified Rankin Scale | |||
| Median score (range) | 2 (0-6) | 2 (0-6) | .47 |
| Score, No. (%) | NA | ||
| 0 | 6 (10.0) | 4 (14.8) | |
| 1 | 20 (33.3) | 6 (22.2) | |
| 2 | 15 (25.0) | 6 (22.2) | |
| 3 | 9 (15.0) | 2 (7.4) | |
| 4 | 2 (3.3) | 2 (7.4) | |
| 5 | 5 (8.3) | 3 (11.1) | |
| 6 | 3 (5.0) | 4 (14.8) | |
| Additional variables, No./Total No. (%)a,b | |||
| Self-reported substantial fatigue | 16/55 (29.1) | 3/23 (13.0) | .13 |
| Self-reported substantial pain | 15/55 (27.3) | 1/23 (4.3) | .03 |
| Self-reported poor mental status ≥1 d in the past monthc | 18/50 (36.0) | 5/22 (22.7) | .27 |
Abbreviation: NA, not applicable.
a
Does not include 1 patient with evidence of Zika virus infection in a comatose state, as well as 3 patients with and 4 patients without evidence of Zika virus infection who died before the 6-month disability follow-up.
b
Does not include 1 patient with evidence of Zika virus infection who declined to answer additional variable questions.
c
Does not include an additional 5 patients with and 1 patient without evidence of Zika virus infection interviewed before implementation of the question on mental health status.