Table 2.
Parameters | Refrigerated temperature (4 ± 1°C) |
Room temperature (25 ± 2°C/60 ± 5% RH) |
|||||
---|---|---|---|---|---|---|---|
0 month | 2 months | 4 months | 6 months | 2 months | 4 months | 6 months | |
Jss (µg/cm2/h) | 20.10±3.761 | 26.74±1.180 | 26.16±2.409 | 25.80±1.229 | 23.99±0.784 | 26.43±3.301 | 27.08±0.890 |
Kp (cm/h) × 10−3 | 12.00±0.002 | 16.00±0.001 | 15.00±0.001 | 15.00±0.001 | 14.00±0.001 | 16.00±0.002 | 16.00±0.001 |
Drug content (%) | 97.33±0.722 | 97.10±1.905 | 96.57±0.185 | 95.14±0.698 | 97.23±0.554 | 95.51±0.845 | 94.96±0.320 |
Note: Each value represents the mean ± SD (n=3).
Abbreviations: Jss, steady state flux; Kp, permeability coefficient; RH, relative humidity.