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. Author manuscript; available in PMC: 2018 Dec 1.
Published in final edited form as: Anticancer Res. 2017 Dec;37(12):6583–6591. doi: 10.21873/anticanres.12115

Figure 1.

Figure 1.

ESE-1 knockdown inhibits transformation properties in trastuzumab resistant HER2+ cell lines. A, B. Stable ESE-1 knockdown inhibits proliferation in trastuzumab resistant HER2+ cell lines BT474-HR20 and SKBR3-Pool2 cell line. Proliferation was measured via trypan blue exclusion method by Vicell. C, D, E, F. Downregulation of ESE-1 inhibits clonogenicity, and soft agar colony formation in the two resistant sublines. Data represented is cumulative of three independent replicates. Error bars represent mean +/− SEM derived from three independent experiments.